A Case of Hyaluronic Acid Induced Blindness With Ophthalmoplegia and Ptosis. Issue 6 (November 2018)

• Record Type: Journal Article
• Authors: Chen, Hui; Wang, Huan; Yang, Zhenglin
• Is Part Of: Ophthalmic plastic and reconstructive surgery. Volume 34:Issue 6(2018)
• Publication Date: 2018-11
• Subjects: Eye -- Surgery -- Periodicals; Ophthalmic plastic surgery -- Periodicals; Reconstructive Surgical Procedures -- Periodicals; Ophthalmologic Surgical Procedures -- Periodicals; Ophthalmology -- Periodicals; Surgery -- Periodicals; 617.70592
• DOI: 10.1097/IOP.0000000000001234
• Languages: English
• ISSNs: 0740-9303

Abstract

Abstract : Hyaluronic acid injection can lead to skin necrosis, visual loss, and other complications. The blindness with ophthalmoplegia and ptosis is a rare, but terrible and devastating complication. The disfigured appearance usually has significant impact on patient's social life. There is no standard treatment. A patient with hyaluronic acid induced blindness, ophthalmoplegia, and ptosis is reported. Six days after the onset, peribulbar/retrobulbar injections of high dosage hyaluronidase were performed. The orbital edema and ptosis immediately improved. The ophthalmoplegia and ptosis improved significantly within a month and resolved completely within 3 months, although the right vision remained blind. Peribulbar/retrobulbar injection of hyaluronidase is a potential rescue therapy for the hyaluronic acid induced ophthalmoplegia and ptosis. Abstract : After combined salvage treatments including retrobulbar hyaluronidase injections, the ophthalmoplegia and ptosis improved significantly within a month, and resolved within three months.Supplemental Digital Content is available in the text.