A Behavioral Physical Activity Intervention to Manage Moderate and Severe Fatigue Among Head and Neck Cancer Patients—Pre-efficacy Study in the National Institutes of Health ORBIT Model. Issue 1 (January 2019)

• Record Type: Journal Article
• Authors: Wang, Hsiao-Lan; McMillan, Susan C.; Vijayakumar, Nisha; McDonald, Sally; Huang, Li-Ting; Gwede, Clement; Padhya, Tapan; Russell, Jeffery; Vondruska, Karen; Buck, Harleah G.; Huang, Yangxin; Visovsky, Connie
• Is Part Of: Cancer nursing. Volume 42:Issue 1(2019)
• Publication Date: 2019-01
• Subjects: Cancer-related fatigue -- Exergame -- Fitness tests -- Head and neck cancer -- Physical activity; Cancer -- Nursing -- Periodicals; 610.736
• DOI: 10.1097/NCC.0000000000000568
• Languages: English
• ISSNs: 0162-220X

Abstract

Abstract : Background: Cancer-related fatigue (CRF) reduces head and neck cancer (HNC) survival rates and is the most common, severe, and distressing symptom negatively impacting activities of daily living (ADLs) dependence among HNC patients. These patients remain physically inactive after their cancer treatment, although there is consensus that physical activity mitigates CRF in cancer patients. Objective: A home-based personalized behavioralp hysicala ctivity intervention withfit ness gradedm otione xergames (PAfitME) was evaluated for its intervention components, intervention delivery mode, and intervention contact time/duration with initial assessment of the feasibility, acceptability, safety, and outcomes. Methods: This study (N = 8) was a single-group, pre-post design to evaluate a 6-week PAfitME at the end of HNC treatment. Health outcomes were CRF, ADL dependence, and fitness performance. Behavioral outcomes were exergame adherence. Results: Positive health and behavioral outcomes support the PAfitME protocol including intervention components, intervention delivery mode, and intervention contact times/duration. The PAfitME intervention is feasible and acceptable with promising adherence rates. No adverse events were reported. There was marked improvement in CRF, ADL dependence, cardiorespiratory fitness, balance, muscle strength, and shoulder forward flexion, with large to moderate effect sizes as a result of the PAfitME intervention. Conclusion: The PAfitME protocol is ready for additional testing in a randomized clinical trial. Implications for Practice: The PAfitME intervention is a nurse-led nonpharmacological intervention. It can be integrated into home care or telehealth care for HNC patients at the end of their cancer treatment once effectiveness is established.