Chemokine Receptor 4 Expression in Primary Sjögren's Syndrome. (November 2018)

• Record Type: Journal Article
• Authors: Cytawa, Wojciech; Kircher, Stefan; Schirbel, Andreas; Shirai, Takahiro; Fukushima, Kazuhito; Buck, Andreas K.; Wester, Hans-Jürgen; Lapa, Constantin
• Is Part Of: Clinical nuclear medicine. Volume 43:Number 11(2018)
• Publication Date: 2018-11
• Subjects: CXCR4 -- lymphoma -- PET -- Sjögren's syndrome; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000002258
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: 68 Ga-pentixafor is a novel radioligand of C-X-C motif chemokine receptor 4. A 55-year-old woman with a history of primary Sjögren's syndrome underwent 68 Ga-pentixafor PET/CT for staging of lymphoma originating from mucosa-associated lymphoid tissue. Whereas no lymphoma manifestation could be detected, imaging revealed bilateral intense radiotracer uptake in both parotid and submandibular salivary glands, consistent with inflammatory cell infiltration.