Nevogenesis: A Benign Metastatic Process?. (31st March 2011)

• Record Type: Journal Article
• Authors: Ross, Andrew L.; Sanchez, Margaret I.; Grichnik, James M.
• Other Names: Firooz A. Academic Editor.; Camacho F. M. Academic Editor.; Val Bernal J. F. Academic Editor.
• Is Part Of: ISRN dermatology. Volume 2011(2011)
• Publication Date: 2011-03-31
• Subjects: Dermatology -- Periodicals; Skin Diseases; Dermatology; Dermatology; Periodicals; 616.5
• DOI: 10.5402/2011/813513
• Languages: English
• ISSNs: 2090-4592

Abstract

Abstract : It is generally accepted that cutaneous nevogenesis is a localized event that occurs exclusively in the dermis and/or epidermis. However, the discovery of nevocytes circulating in the peripheral blood suggests that other, more systemic, benign metastatic processes could also be involved. The theoretical role of lymphatic and hematogenous dissemination of loosely adherent, immature nevus progenitor cells in the development of nodal nevi and eruptive melanocytic nevi will be reviewed.