BiCl3-Mediated direct functionalization of unsaturated C–C bonds with an electrophilic SCF2PO(OEt)2 reagent. Issue 60 (2nd April 2019)

• Record Type: Journal Article
• Authors: Wang, Jianjun; Xiong, Heng-Ying; Petit, Emilie; Bailly, Laëtitia; Pannecoucke, Xavier; Poisson, Thomas; Besset, Tatiana
• Is Part Of: Chemical communications. Volume 55:Issue 60(2019)
• Page Start: 8784
• Page End: 8787
• Publication Date: 2019-04-02
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c9cc01851d
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A general access to challenging and unprecedented C(sp)–, C(sp 2 )– and C(sp 3 )–SCF2 PO(OEt)2 bonds via a BiCl3 mediated transformation. Abstract : A transition metal-free approach was developed for the direct difunctionalization of disubstituted alkynes and terminal alkenes with concomitant formation of C–SCF2 PO(OEt)2 and C–Cl bonds. The BiCl3 -mediated reaction offered access to high value-added functionalized scaffolds in a single operation under mild conditions. Extension to SCF2 PO(OEt)2 -containing alkynes was also studied.