Efficient production of coenzyme Q10 from acid hydrolysate of sweet sorghum juice by Rhodobacter sphaeroides. Issue 39 (18th July 2019)

• Record Type: Journal Article
• Authors: Wang, Y.; Chen, S.; Liu, J.; Lv, P.; Cai, D.; Zhao, G.
• Is Part Of: RSC advances. Volume 9:Issue 39(2019)
• Page Start: 22336
• Page End: 22342
• Publication Date: 2019-07-18
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c9ra03964c
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : An efficient coenzyme Q10 production from sweet sorghum juice was achieved, and a high product yield (205.83 mg L −1 sweet sorghum juice) was obtained under the optimized fed-batch fermentation. Abstract : In order to achieve efficient bioconversion of biomass-derived sugars, acid hydrolysate of sweet sorghum juice (SSJAH) containing abundant fermentable sugars was used for coenzyme Q10 (CoQ10 ) fermentation by Rhodobacter sphaeroides CQ-09-1. The synthesis of CoQ10 was facilitated when the initial concentration of total sugar was 80.00 g L −1 . And the highest CoQ10 titer was obtained when the pH and temperature were maintained at 7.00 and 30.00 °C, respectively. Moreover, corn steep powder (CSP) was proved to be an efficient nitrogen & salt supplement to SSJAH. Under the optimized conditions, the titer of CoQ10 reached 141.95 mg L −1 in a fed-batch fermentation. The CoQ10 titer reported was about two times higher than that obtained in the previous study using wild strains. This process introduces a potential way to produce CoQ10 using the concept of biorefinery, while making full use of sweet sorghum juice (SSJ).