Condensations based on 5‐(indol‐3‐yl)‐pyrrolidin‐2‐thiones. Issue 4 (20th November 2018)

• Record Type: Journal Article
• Authors: Sadovoy, Andrey V.; Kattsyna, Veronica V.; Protopopova, Polina S.; Nelyubina, Yulia V.; Pavlov, Alexander A.; Kochetkov, Konstantin A.; Sviridova, Lyudmila A.
• Is Part Of: Heteroatom chemistry. Volume 29:Issue 4(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-11-20
• Subjects: 5‐indolyl‐2‐aminomethylpyrrolidines -- 5‐indolyl‐2‐dicyanomethylenepyrrolidines -- 5‐indolyl‐2‐methylthiopyrrolinium salts -- stereoelectronic demands; Heterocyclic chemistry -- Periodicals; 547.59
• DOI: 10.1002/hc.21451
• Languages: English
• ISSNs: 1042-7163

Abstract

Abstract: New activated indolylpyrrolidones—their methylthiopyrrolinium salts—in the reactions with several CH‐acids were studied. 2‐Nitromethylene‐ and 2‐dicyanomethyleneindolylpyrrolidines were obtained from 5‐indolyl‐2‐methylthiopyrrolinium salts with good yields. The reduction in these nitro compounds yields the respective aminomethylpyrolidines. The rigid structure of the starting compounds has significant stereoelectronic requirements of nucleophilic agents.