Jejunal GIST: Hunting down an unusual cause of gastrointestinal bleed using double balloon enteroscopy. A case report. (2019)

• Record Type: Journal Article
• Authors: Dualim, Diana Mellisa; Loo, Guo Hou; Rajan, Reynu; Nik Mahmood, Nik Ritza Kosai
• Is Part Of: International journal of surgery case reports. Volume 60(2019)
• Page Start: 303
• Page End: 306
• Publication Date: 2019
• Subjects: Laparoscopic -- Obscure GI bleeding -- Double-balloon enteroscopy -- Small bowel bleeding -- Gastrointestinal stromal tumour -- Capsule endoscopy; Surgery -- Periodicals; Surgical Procedures, Operative -- Periodicals; Surgery; Electronic journals; Periodicals; 617.005
• DOI: 10.1016/j.ijscr.2019.06.053
• Languages: English
• ISSNs: 2210-2612

Abstract

Highlights: Bleeding jejunal GIST is very rare with only a handful of published case reports. Double-balloon enteroscopy and capsule endoscopy can be used to diagnose bleeding small intestine GIST. Occult small bowel bleeding can go undetected for years. Age is one of the determining factors for the type of small bowel pathology detected. Surgical resection remains the mainstay treatment for GIST. Laparoscopic surgery offers similar oncologic outcomes as an open surgery. Abstract: Introduction: Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal neoplasms of the alimentary tract but accounts for only 0.1–3% of all gastrointestinal neoplasms. The most common presentation of GISTs is acute or chronic gastrointestinal bleeding, in which the patient presents with symptomatic anaemia. Presentation of case: With that in mind, we describe a 66-year-old man who presented with recurrent episodes of obscure gastrointestinal bleeding for two years. Video capsule endoscopy (VCE) showed several small telangiectasias in the proximal small bowel. Oral route double-balloon enteroscopy (DBE) revealed abnormal mucosa 165 cm from incisor with central ulceration and vascular component. He subsequently underwent surgical excision. The histopathological report confirmed the diagnosis of GIST arising from the jejunum. During his clinic follow up, he remains symptom-free with no evidence of recurrence. Discussion: The diagnosis of bleeding small intestine GISTs can be challenging as these are inaccessible by conventional endoscopy. Imaging modalities such as double-balloon enteroscopy, capsule endoscopy, CT angiography, intravenous contrast-enhanced multidetector row CT (MDCT) and magnetic resonance enterography (MRE) have been used to assist in the diagnosis of bleeding small intestine GISTs. The mainstay of management for small intestine GIST is complete surgical excision. Conclusion: Bleeding jejunal GIST is very rare and only a handful of case reports have been published. The mainstay of management for small intestine GIST is complete surgical excision. It is essential to obtain a complete excision of localised disease and avoiding tumour spillage in order to reduce the risk of local recurrence and metastatic spread of GISTs.