Cartilage wear patterns in severe osteoarthritis of the trapeziometacarpal joint: a quantitative analysis. Issue 8 (August 2019)

• Record Type: Journal Article
• Authors: Miyamura, S.; Oka, K.; Sakai, T.; Tanaka, H.; Shiode, R.; Shimada, S.; Mae, T.; Sugamoto, K.; Yoshikawa, H.; Murase, T.
• Is Part Of: Osteoarthritis and cartilage. Volume 27:Issue 8(2019)
• Page Start: 1152
• Page End: 1162
• Publication Date: 2019-08
• Subjects: Cartilage wear -- First metacarpal -- Laser scanner -- Osteoarthritis -- Trapeziometacarpal joint -- Trapezium; Osteoarthritis -- Periodicals; Cartilage -- Periodicals; Osteoarthritis -- Periodicals; Cartilage -- Periodicals; Arthrose -- Périodiques; Articulations -- Maladies -- Périodiques; 616.7223005
• DOI: 10.1016/j.joca.2019.03.006
• Languages: English
• ISSNs: 1063-4584

Abstract

Summary: Objective: The present quantitative study aimed to assess the three-dimensional (3-D) cartilage wear patterns of the first metacarpal and trapezium in the advanced stage of osteoarthritis (OA) and compare cartilage measurements with radiographic severity. Design: Using 19 cadaveric trapeziometacarpal (TMC) joints, 3-D cartilage surface models of the first metacarpal and trapezium were created with a laser scanner, and 3-D bone surface model counterparts were similarly created after dissolving the cartilage. These two models were superimposed, and the interval distance on the articular surface as the cartilage thickness was measured. All measurements were obtained in categorized anatomic regions on the articular surface of the respective bone, and we analyzed the 3-D wear patterns on the entire cartilage surface. Furthermore, we compared measurements of cartilage thickness with radiographic OA severity according to the Eaton grading system using Pearson correlation coefficients ( r ). Results: In the first metacarpal, the cartilage thickness declined volarly (the mean cartilage thickness of the volar region was 0.32 ± 0.16 mm, whereas that of the dorsal region was 0.53 ± 0.18 mm). Conversely, the cartilage evenly degenerated throughout the articular surface of the trapezium. Measurements of the categorized regions where cartilage thinning was remarkable exhibited statistical correlations with radiographic staging ( r = −0.48 to −0.72). Conclusions: Our findings indicate that cartilage wear patterns differ between the first metacarpal and trapezium in the late stage of OA. There is a need for further studies on cartilage degeneration leading to symptomatic OA in the TMC joint.