Design, synthesis, and nematicidal activities of novel 1, 3-thiazin(thiazol)-4-one derivatives against Meloidogyne incognita. Issue 5 (May 2019)

• Record Type: Journal Article
• Authors: Jia, Haowu; Guo, Wei; Li, Wei; Li, Tingfang; Chen, Xiulei; Li, Zhong; Xu, Xiaoyong
• Is Part Of: Journal of chemical research. Volume 43:Issue 5/6(2019)
• Page Start: 161
• Page End: 169
• Publication Date: 2019-05
• Subjects: 1 -- 3-thiazin(thiazol)-4-one -- in vivo -- Meloidogyne spp -- nematicide; Chemistry -- Research -- Periodicals; Chemistry -- Periodicals; 540.5
• DOI: 10.1177/1747519819857506
• Languages: English
• ISSNs: 1747-5198

Abstract

Four series of novel 1, 3-thiazin(thiazol)-4-one derivatives were synthesized by Suzuki coupling. Preliminary bioassays showed that most of the synthesized compounds exhibited good inhibitory activity in vivo against root-knot nematodes, Meloidogyne spp . at 20 mg L −1 . Among the tested compounds, we found that two compounds displayed 46.4% and 41.4% inhibitory activity even at 1 mg L −1, respectively.