Fluorescence Sensors for Fe3+ Ion with High Selectivity and Sensitivity and Bioimaging in Living Cells. Issue 39 (24th October 2018)

• Record Type: Journal Article
• Authors: Xue, Kun; Wang, Peng; Dong, Wenling; Luo, Xiaohan; Cheng, Pengfei; Xu, Kuoxi
• Is Part Of: ChemistrySelect. Volume 3:Issue 39(2018)
• Page Start: 11081
• Page End: 11086
• Publication Date: 2018-10-24
• Subjects: Quinoline derivatives -- Synthesis -- Fluorescence sensor -- Fe3+ detection -- Fluorescence imaging; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/slct.201802718
• Languages: English
• ISSNs: 2365-6549

Abstract

Abstract: Two fluorescence sensors L1 and L2 were designed and synthesized. They exhibited fluorescence emission at 570 nm in DMSO/H2 O (Tris buffer, pH=7.4, v/v=5: 1). The sensors L1 and L2 displayed excellent sensitivity specific toward Fe 3+ in comparison to other environmentally important metal ions, including Fe 2+ ions, and the detection limit was as low as 5.11×10 −8 M. Furthermore, living PC‐12 cell imaging experiments indicated that the sensors L1 and L2 were cell‐permeable and they could be used to detect intracellular Fe 3+ ions. Abstract : Two novel fluorescence sensors exhibited excellent sensitivity specific toward Fe 3+ ion at 570 nm in DMSO/H2 O (Tris buffer, pH=7.4, v/v=5: 1). Furthermore, living PC‐12 cell imaging experiments indicated that the sensors were cell‐permeable and they could be used to detect intracellular Fe 3+ ions.