Unusual structural characteristics of the Mycobacterium tuberculosis pentapeptide repeat protein MfpA. Issue 3 (2010)
- Record Type:
- Journal Article
- Title:
- Unusual structural characteristics of the Mycobacterium tuberculosis pentapeptide repeat protein MfpA. Issue 3 (2010)
- Main Title:
- Unusual structural characteristics of the Mycobacterium tuberculosis pentapeptide repeat protein MfpA
- Authors:
- Khrapunov Khrapunov, S. S.
Cheng Cheng, H. H.
Hegde Hegde, S. S.
Blanchard Blanchard, J. J.
Brenowitz Brenowitz, M. M. - Abstract:
- Abstract : The solution structure and refolding of the Mycobacterium tuberculosis pentapeptide repeat protein MfpA was explored by fluorescence and circular dichroism spectroscopy. Our results show that MfpA exists in two stable structural forms which exclusively favor dimer or oligomer formation. The structural malleability of MfpA may provide a novel target for drug discovery.
- Is Part Of:
- Spectroscopy. Volume 24:Issue 3/4(2010)
- Journal:
- Spectroscopy
- Issue:
- Volume 24:Issue 3/4(2010)
- Issue Display:
- Volume 24, Issue 3/4 (2010)
- Year:
- 2010
- Volume:
- 24
- Issue:
- 3/4
- Issue Sort Value:
- 2010-0024-NaN-0000
- Page Start:
- 339
- Page End:
- 341
- Publication Date:
- 2010
- Subjects:
- Protein structure -- protein stability -- drug resistance
- DOI:
- 10.3233/SPE-2010-0449 ↗
- Languages:
- English
- ISSNs:
- 0712-4813
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library HMNTS - ELD Digital store
- Ingest File:
- 11120.xml