Biosourced Ligands from Isosorbide for the Ethylation of Aldehydes or Alkynylation of Imines. Issue 10 (8th August 2016)

• Record Type: Journal Article
• Authors: Huynh, Khanh‐Duy; Ibrahim, Houssein; Bouchardy, Lucie; Bournaud, Chloée; Kolodziej, Emilie; Toffano, Martial; Vo‐Thanh, Giang
• Is Part Of: Asian journal of organic chemistry. Volume 5:Issue 10(2016)
• Page Start: 1242
• Page End: 1246
• Publication Date: 2016-08-08
• Subjects: alkynylation -- asymmetric catalysis -- isosorbide -- ligand design -- synthetic methods; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; 547.005
• DOI: 10.1002/ajoc.201600291
• Languages: English
• ISSNs: 2193-5807

Abstract

Abstract: β‐Amino alcohol and diamine ligands were prepared from isosorbide as a chiral renewable resource. The efficiencies of these ligands were evaluated for the metal‐catalyzed enantioselective ethylation of aldehydes and the alkynylation of aldimines. Abstract : The efficiencies of isosorbide‐derived β‐amino alcohol and diamine ligands were evaluated for the metal‐catalyzed ethylation of aldehydes and the alkynylation of aldimines. Good yields and up to 80 % ee were observed.