ChemInform Abstract: An Organocatalytic Domino Michael‐Alkylation Reaction: Highly Enantioselective Construction of Spiro‐Cyclopentanoneoxindoles and Tetronic Acid Scaffolds. Issue 15 (April 2015)

• Record Type: Journal Article
• Authors: Zhou, Jing; Wang, Qi‐Lin; Peng, Lin; Tian, Fang; Xu, Xiao‐Ying; Wang, Li‐Xin
• Is Part Of: ChemInform. Volume 46:Issue 15(2015)
• Page Start: no
• Page End: no
• Publication Date: 2015-04
• Subjects: spirocyclic compounds (heterocyclic compounds) -- indole derivatives, isoindole derivatives -- diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism) -- organocatalysis; Chemistry -- Abstracts -- Periodicals; 540.5
• DOI: 10.1002/chin.201515132
• Languages: English
• ISSNs: 0931-7597

Abstract

Abstract: The title reaction of methyleneindolinones with ketoester (II) results in the formation of various spiro‐cyclopentanoneoxindoles which are obtained in high yields, good diastereoselectivities and excellent enantioselectivities via α‐alkylation.