Peritoneal Keratin Granulomatosis Is a Clinical and Radiological Mimicker of Endometrial Adenocarcinoma With Peritoneal Involvement. (October 2019)

• Record Type: Journal Article
• Authors: Wong, Jahg; Roy, Simon F.; Gougeon, François
• Is Part Of: International journal of surgical pathology. Volume 27:Number 7(2019)
• Page Start: 757
• Page End: 759
• Publication Date: 2019-10
• Subjects: peritoneal keratin granuloma -- endometrioid adenocarcinoma -- squamous differentiation -- diagnostic pitfall -- mimicker; Pathology, Surgical -- Periodicals; 617.07
• DOI: 10.1177/1066896919849672
• Languages: English
• ISSNs: 1066-8969

Abstract

Peritoneal keratin granulomatosis is a rare tumor-like lesion caused by deposition of tumor-produced keratin. It may be associated with endometrial or ovarian endometrioid adenocarcinoma, atypical polypoid adenomyoma of the endometrium, or ruptured mature teratomas of the ovary. We present 2 cases of peritoneal keratin granulomatosis associated with FIGO (International Federation of Gynecology and Obstetrics) stage 1 endometrial adenocarcinoma. This entity can mimic advanced-stage disease clinically and radiologically, as it did in those cases, and constitutes a diagnostic pitfall that pathologists and surgeons must be aware.