Bench‐Stable N‐Heterocyclic Carbene Nickel Precatalysts for C−C and C−N Bond‐Forming Reactions. Issue 13 (2nd May 2018)

• Record Type: Journal Article
• Authors: Strieth‐Kalthoff, Felix; Longstreet, Ashley R.; Weber, Jessica M.; Jamison, Timothy F.
• Is Part Of: ChemCatChem. Volume 10:Issue 13(2018)
• Page Start: 2873
• Page End: 2877
• Publication Date: 2018-05-02
• Subjects: homogeneous catalysis -- hydroalkenylation -- N-heterocyclic carbene ligands -- nickel -- precatalyst; Catalysis -- Periodicals; 541.39505
• DOI: 10.1002/cctc.201800454
• Languages: English
• ISSNs: 1867-3880

Abstract

Abstract: Herein, we introduce a new class of bench‐stable N ‐heterocyclic carbene (NHC) nickel‐precatalysts for homogeneous nickel‐catalysis. The nickel(II) complexes are readily activated to Ni 0 in situ under mild conditions, via a proposed Heck‐type mechanism. The precatalysts are shown to facilitate carbonyl‐ene, hydroalkenylation, and amination reactions. Abstract : NHC Nickel Precatalysts : Bench‐stable N ‐heterocyclic carbene (NHC) nickel(II) precatalysts have been designed to undergo a Heck‐like mode of activation under mild conditions. Catalytic efficiency is demonstrated with carbonyl‐ene, hydroalkenylation, and amination reactions.