Long-term intermittent low-frequency repetitive transcranial magnetic stimulation effectively controls seizures in two drug-free adolescent patients. Issue 8 (August 2019)

• Record Type: Journal Article
• Authors: Li, Hongzhan; Wang, Chunyan; Zhang, Shaotian; Zhang, Chengliang; Lu, Rulan; Yun, Wenwei; Zhou, Xianju
• Is Part Of: Journal of international medical research. Volume 47:Issue 8(2019)
• Page Start: 3968
• Page End: 3971
• Publication Date: 2019-08
• Subjects: Epilepsy -- repetitive transcranial magnetic stimulation -- low frequency -- cortical dysplasia -- adolescent -- convulsion -- seizure; Medicine -- Periodicals; Pharmacology -- Periodicals; 610.5
• DOI: 10.1177/0300060519862950
• Languages: English
• ISSNs: 0300-0605

Abstract

Recently, repetitive transcranial magnetic stimulation (rTMS) has been widely used for treating neurological and psychiatric diseases. Low-frequency rTMS is used to effectively control the occurrence of seizures, including medication-refractory epilepsy and cortical dysplasia or neocortical epilepsy. However, there have been no reports on the effects of long-term rTMS on epilepsy. We observed the clinical effects of long-term rTMS in two drug-free adolescent epileptic patients with a preference for non-drug therapy. The two drug-free adolescent patients, who underwent intermittent low-frequency rTMS treatment for 36 weeks, obtained effective control of seizures (including episode and severity). However, a systematic study is required to confirm our observations.