A pre-post pilot study of electronic cigarettes to reduce smoking in people with severe mental illness. Issue 6 (10th July 2018)

• Record Type: Journal Article
• Authors: Hickling, Lauren M.; Perez-Iglesias, Rocio; McNeill, Ann; Dawkins, Lynne; Moxham, John; Ruffell, Tamatha; Sendt, Kyra-Verena; McGuire, Philip
• Is Part Of: Psychological medicine. Volume 49:Issue 6(2019)
• Page Start: 1033
• Page End: 1040
• Publication Date: 2018-07-10
• Subjects: Acceptability, -- e-cigarette, -- electronic cigarette, -- harm reduction, -- psychosis, -- schizophrenia, -- smoking, -- tobacco; Psychiatry -- Periodicals; Medicine and psychology -- Periodicals; Clinical psychology -- Periodicals; 616.89
• DOI: 10.1017/S0033291718001782
• Languages: English
• ISSNs: 0033-2917

Abstract

Abstract: Background: Smoking is the largest single contributor to poor physical health and increased mortality in people with serious mental illnesses. The aim of the study was to investigate the utility of electronic cigarettes (e-cigarettes) as a harm reduction intervention in this population. Method: Fifty tobacco smokers with a psychotic disorder were enrolled onto a 24-week pilot study (ClinicalTrials.gov: NCT02212041) investigating the efficacy of a 6-week free e-cigarette intervention to reduce smoking. Cigarette and e-cigarette use was self-reported at weekly visits, and verified using carbon monoxide tests. Psychopathology, e-cigarette acceptability and adverse effects were assessed using standardised scales. Results: There was a significant (⩾50%) reduction in cigarettes consumed per day between baseline and week 6 [ F (2.596, 116.800) = 25.878, p < 0.001], and e-cigarette use was stable during this period [ F (2.932, 46.504) = 2.023, p = 0.115]. These changes were verified by significant carbon monoxide reductions between these time points [ F (3.335, 126.633) = 5.063, p = 0.002]. Conclusions: The provision of e-cigarettes is a potentially useful harm reduction intervention in smokers with a psychotic disorder.