Therapy-induced small-cell disease: from mouse to man and back. Issue 11 (November 2018)

• Record Type: Journal Article
• Authors: Grabowska, Magdalena; Matusik, Robert
• Is Part Of: Nature reviews. Volume 15:Issue 11(2018)
• Page Start: 662
• Page End: 663
• Publication Date: 2018-11
• Subjects: Urology -- Periodicals; Clinical medicine -- Periodicals; Urology -- Diseases -- Diagnosis -- Periodicals; Urology -- Diseases -- Treatment -- Research -- Periodicals; 616.6005
• DOI: 10.1038/s41585-018-0084-z
• Languages: English
• ISSNs: 1759-4812

Abstract

With the emergence of increasingly potent androgen deprivation therapy, rates of treatment-emergent small-cell neuroendocrine prostate cancer are increasing. In a recent prospective study, Aggarwal and colleagues defined the frequency and clinical and genomic characteristics of these tumours.