The importance of genetic counselling in genome-wide sequencing. Issue 12 (December 2018)

• Record Type: Journal Article
• Authors: Elliott, Alison; Friedman, Jan
• Is Part Of: Nature reviews. Volume 19:Issue 12(2018)
• Page Start: 735
• Page End: 736
• Publication Date: 2018-12
• Subjects: Genetics -- Periodicals; 576.505
• DOI: 10.1038/s41576-018-0057-3
• Languages: English
• ISSNs: 1471-0056

Abstract

Genome-wide sequencing (GWS) is the most sensitive test available for detecting pathogenic genetic variants. In line with guidelines in North America and Europe, best clinical practice requires GWS to be implemented as a holistic clinical service that includes both pre-test and post-test genetic counselling. Genome-wide sequencing (GWS) is the most sensitive test available for detecting pathogenic genetic variants but it generates complex results. It is important, therefore, that individuals undergoing GWS are offered both pre-test and post-test genetic counselling.