Chemoprevention of Barrett's oesophagus: a step closer with PPIs and aspirin. Issue 12 (December 2018)

• Record Type: Journal Article
• Authors: Husain, Nisreen; El-Serag, Hashem
• Is Part Of: Nature reviews. Volume 15:Issue 12(2018)
• Page Start: 728
• Page End: 730
• Publication Date: 2018-12
• Subjects: Cancer -- Treatment -- Periodicals; Cancer -- Periodicals; Oncology -- Periodicals; 616.994
• DOI: 10.1038/s41571-018-0096-x
• Languages: English
• ISSNs: 1759-4774

Abstract

Chemoprevention for patients with Barrett's oesophagus remains a controversial topic. Results of the first randomized trial of chemoprevention using a proton pump inhibitor with or without aspirin were recently reported. We highlight strengths and weaknesses in the design of the trial and discuss the clinical implications of the findings.