An elevated creatine kinase in the context of influenza A infection and sickle cell trait. Issue 1 (26th June 2019)

• Record Type: Journal Article
• Authors: Bamber, H.; Rudge, B.; Vercueil, A.
• Is Part Of: Anaesthesia reports. Volume 7:Issue 1(2019)
• Page Start: 57
• Page End: 59
• Publication Date: 2019-06-26
• Subjects: acute kidney injury -- acute tubular necrosis: diagnosis -- influenza -- rhabdomyolysis -- sickle cell trait; Anesthesiology -- Periodicals; 617.9605
• DOI: 10.1002/anr3.12017
• Languages: English
• ISSNs: 2637-3726

Abstract

Summary: We describe the case of a 37‐year‐old normally fit and well man who presented to hospital with fever, lethargy and myalgia. He was found to have a creatine kinase level of over 1 million IU.l −1 . He initially underwent fluid resuscitation, but despite this his renal function declined and he required continuous veno‐venous haemodiafiltration. Subsequent testing revealed a positive viral swab for influenza A and that he was a carrier of sickle cell trait. We review the literature for previous reports describing this association and demonstrate the rarity of such a presentation.