Diagnostic accuracy of the Thai version of the Mini‐Addenbrooke's Cognitive Examination as a mild cognitive impairment and dementia screening test. Issue 4 (30th January 2019)

• Record Type: Journal Article
• Authors: Charernboon, Thammanard
• Is Part Of: Psychogeriatrics. Volume 19:Issue 4(2019)
• Page Start: 340
• Page End: 344
• Publication Date: 2019-01-30
• Subjects: Alzheimer's disease -- cognition -- dementia -- mild cognitive impairment -- neuropsychological test; Geriatric psychiatry -- Periodicals; 618.9768905
• DOI: 10.1111/psyg.12417
• Languages: English
• ISSNs: 1346-3500

Abstract

Abstract : Aim: To examine the diagnostic accuracy of the Thai version of the Mini‐Addenbrooke's Cognitive Examination (MACE‐T) for detecting mild cognitive impairment and dementia. Methods: Participants consisted of 60 controls, 40 people with mild cognitive impairment (MCI) and 48 people with dementia. All participants completed the Thai version of the Addenbrooke's Cognitive Examination – III (ACE‐T) and the MACE‐T scores were obtained from items within the ACE‐T. Results: A cut‐off score of 21/22 detected MCI with a sensitivity of 95% (95% confidence interval (CI): 86.1–100) and specificity of 85% (95% CI: 77.8–93.4). A cut‐off score of 16/17 detected dementia with a sensitivity and specificity of 95.8% (95% CI: 88.2–100) and 85% (95% CI: 76.4–89.7), respectively. Using Bayes theorem, the MACE‐T demonstrated high negative predictive values (> 94%) for diagnosing MCI and dementia, independent of their prevalence rates. Education was the only significant predictor of performance in the MACE‐T. Conclusion: The MACE‐T is a good short cognitive screening test with high diagnostic accuracy for screening for MCI and dementia.