No association of serum PSA with vitamin D or total oxidant-antioxidant capacity in healthy men. (3rd July 2019)

• Record Type: Journal Article
• Authors: Toprak, Burak; Colak, Ayfer; Yalcin, Hulya; Yildirim, Mustafa
• Is Part Of: Aging male. Volume 22:Number 3(2019)
• Page Start: 214
• Page End: 217
• Publication Date: 2019-07-03
• Subjects: Vitamin D -- PSA -- BMI -- smoking -- total oxidant status; Aging -- Periodicals; Men -- Periodicals; Gerontology -- Periodicals; Men -- Health and hygiene -- Periodicals; Aging -- periodicals; Geriatric -- periodicals; Men -- periodicals; Aged -- periodicals; Aged, 80 and over -- periodicals; 612.67
• DOI: 10.1080/13685538.2018.1491026
• Languages: English
• ISSNs: 1368-5538

Abstract

Abstract: Background and aim: Vitamin D deficiency and oxidative stress were suggested to be related to prostate cancer risk. We aimed to investigate the association of serum PSA concentration with vitamin D and total oxidant/antioxidant levels. Materials and methods: A total of 95 healthy men were enrolled for the cross sectional study. Serum PSA, 25(OH)D, serum total oxidant status, and total antioxidant status were measured. Results: Serum PSA was significantly negatively correlated with serum total oxidant status ( r = −0.309, p = .003) but there was no significant correlation between PSA and 25(OH)D ( p = .383) or total antioxidant levels ( p = .233). After adjustment for age BMI and smoking status with multiple regression analysis, there was no significant association between serum PSA and total oxidant status. Conclusion: We find no evidence for an association between PSA and vitamin D levels or serum total oxidant/antioxidant levels.