Methylene chain ruler for evaluating the regioselectivity of a substrate-recognising oxidation catalyst. Issue 58 (24th June 2019)

• Record Type: Journal Article
• Authors: Teramae, Shota; Kito, Akane; Shingaki, Tomoteru; Hamaguchi, Yu; Yano, Yuuki; Nakayama, Takamori; Kobayashi, Yuko; Kato, Nobuki; Umezawa, Naoki; Hisamatsu, Yosuke; Nagano, Tetsuo; Higuchi, Tsunehiko
• Is Part Of: Chemical communications. Volume 55:Issue 58(2019)
• Page Start: 8378
• Page End: 8381
• Publication Date: 2019-06-24
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c9cc03041g
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : We designed and synthesised Ru porphyrin1a as an oxidation catalyst with substrate recognition sites. The1a catalysed oxidation of substrate7 selectively oxidised the central position of the methylene chain, affording ketone8 as the major product. Abstract : Regioselective C–H oxidation of aliphatic molecules with synthetic catalysts is challenging. We incorporated substrate-recognition sites into a ruthenium porphyrin–heteroaromatic N -oxide catalytic system in order to characterise its regioselectivity for the oxidation of alkanes. This substrate-recognition catalytic reaction exhibits high regioselectivity and high reaction efficiency.