A highly efficient cobalt-catalyzed deuterogenolysis of diboron: Synthesis of deuterated pinacolborane and vinylboronates. Issue 31 (2nd August 2019)

• Record Type: Journal Article
• Authors: Qiao, Lin; Zhang, Lei; Liu, Guixia; Huang, Zheng
• Is Part Of: Tetrahedron. Volume 75:Issue 31(2019)
• Page Start: 4138
• Page End: 4142
• Publication Date: 2019-08-02
• Subjects: Boranes -- Cobalt -- Deuteration -- Deuterogenolysis -- Organoboranates; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tet.2019.03.053
• Languages: English
• ISSNs: 0040-4020

Abstract

Abstract: Highly efficient hydrogenolysis and deuterogenolysis of diboron compounds have been realized by the use of a cobalt catalyst, affording TON up to 48201. Furthermore, a one-pot two-step procedure comprising sequential deuterogenolysis of diboron and deuteroboration of alkynes under the same cobalt catalyst has been developed for the efficient, atom-economical synthesis of deuterated vinylboronates with high deuterium incorporation and excellent regio- and stereoselectivity. Graphical abstract: Image 1