Attributable mortality due to fluoroquinolone and extended-spectrum cephalosporin resistance in hospital-onset Escherichia coli and Klebsiella spp bacteremia: A matched cohort study in 129 Veterans Health Administration medical centers. (August 2019)

• Record Type: Journal Article
• Authors: Suzuki, Hiroyuki; Perencevich, Eli N.; Livorsi, Daniel J.; Alexander, Bruce; Beck, Brice F.; Richardson, Kelly K.; Goto, Michihiko
• Is Part Of: Infection control and hospital epidemiology. Volume 40:Number 8(2019)
• Page Start: 928
• Page End: 931
• Publication Date: 2019-08
• Subjects: Nosocomial infections -- Epidemiology -- Periodicals; Health facilities -- Sanitation -- Periodicals; Hospital buildings -- Sanitation -- Periodicals; Cross Infection -- Periodicals; Epidemiology -- Periodicals; Hospitals -- Periodicals; Infection Control -- Periodicals; 614.44
• DOI: 10.1017/ice.2019.155
• Languages: English
• ISSNs: 0899-823X

Abstract

Abstract: In this cohort of Escherichia coli and Klebsiella spp hospital-onset bacteremia, isolated fluoroquinolone resistance had a larger relative impact on mortality than other phenotypic resistance patterns. This finding may support stewardship efforts targeting unnecessary fluoroquinolone use and increased attention from infection prevention and control departments.