A highly selective fluorogenic substrate for imaging glutathione S-transferase P1: development and cellular applicability in epigenetic studies. Issue 56 (25th June 2019)
- Record Type:
- Journal Article
- Title:
- A highly selective fluorogenic substrate for imaging glutathione S-transferase P1: development and cellular applicability in epigenetic studies. Issue 56 (25th June 2019)
- Main Title:
- A highly selective fluorogenic substrate for imaging glutathione S-transferase P1: development and cellular applicability in epigenetic studies
- Authors:
- Mori, Masaya
Fujikawa, Yuuta
Kikkawa, Manami
Shino, Moeho
Sawane, Mei
Sato, Shiho
Inoue, Hideshi - Abstract:
- Abstract : A highly selective fluorogenic substrate was designed for the specific visualization of intracellular GSTP1 activity in cancer cells. Abstract : Pi-class glutathione S-transferase (GSTP1) is a molecular marker enzyme whose expression level is altered in various malignant tumour tissues. Herein, we report the first highly selective fluorogenic GSTP1 substrate, Ps-TG, and its membrane-permeable derivativePs-TAc, for specific visualization of intracellular GSTP1 activity in cancer cells or epigenetically regulated GSTP1 expression.
- Is Part Of:
- Chemical communications. Volume 55:Issue 56(2019)
- Journal:
- Chemical communications
- Issue:
- Volume 55:Issue 56(2019)
- Issue Display:
- Volume 55, Issue 56 (2019)
- Year:
- 2019
- Volume:
- 55
- Issue:
- 56
- Issue Sort Value:
- 2019-0055-0056-0000
- Page Start:
- 8122
- Page End:
- 8125
- Publication Date:
- 2019-06-25
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c9cc03064f ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 11000.xml