Cobalt(ii)-catalyzed benzylic oxidations with potassium persulfate in TFA/TFAA. Issue 36 (4th July 2019)

• Record Type: Journal Article
• Authors: Li, Tianlei; Li, Jishun; Zhu, Zihao; Pan, Weidong; Wu, Song
• Is Part Of: RSC advances. Volume 9:Issue 36(2019)
• Page Start: 20879
• Page End: 20883
• Publication Date: 2019-07-04
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c9ra03346g
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : A Co-catalyzed C(sp 3 )–H oxygenation reaction to furnish diverse aldehydes from methylarenes in TFA/TFAA is reported. This transformation demonstrated high chemo-selectivity, and tolerated with various methylarenes bearing electron-withdrawing substituents. Abstract : A cobalt-catalyzed C(sp 3 )–H oxygenation reaction to furnish aldehyde was herein reported. This transformation demonstrated high chemo-selectivity, and tolerated various methylarenes bearing electron-withdrawing substituents. This reaction provided rapid access to diverse aldehydes form methylarenes. Notably, TFA/TFAA was used for the first time as a mixed solvent in cobalt-catalyzed oxygenation of benzylic methylenes.