Clinical characteristics and glucose‐lowering drug utilization among patients initiating liraglutide in Denmark: a routine clinical care prescription study. Issue 8 (25th April 2019)

• Record Type: Journal Article
• Authors: Knudsen, Jakob S.; Thomsen, Reimar W.; Pottegård, Anton; Knop, Filip K.; Sørensen, Henrik T.
• Is Part Of: Journal of diabetes. Volume 11:Issue 8(2019)
• Page Start: 690
• Page End: 694
• Publication Date: 2019-04-25
• Subjects: cross‐sectional studies -- diabetes pharmacology -- drug utilization -- glucagon‐like peptide‐1 receptor -- liraglutide; Diabetes -- Periodicals; 618.3646005
• DOI: 10.1111/1753-0407.12919
• Languages: English
• ISSNs: 1753-0393

Abstract

Abstract : Highlights This population‐based real‐world prescription study characterized all new users of liraglutide in northern Denmark from 2009 to 2015. More than half (57%) the patients had liraglutide prescribed as part of drug combinations outside the originally approved indications. Comorbidities or diabetes complications were present in most patients, with the highest prevalence observed among the 73% of initiators who would have been ineligible for the Liraglutide Effect and Action in Diabetes (LEAD) 1‐5 trials that led to liraglutide registration, underscoring the need for further post‐marketing studies.