Catalase-mimetic gold nanoparticles inhibit the antagonistic action of Lactobacillus gasseri toward foodborne enteric pathogens in associative cultures. (3rd April 2019)

• Record Type: Journal Article
• Authors: Zhu, Suqin; Zeng, Mingyong; Guo, Wei; Feng, Guangxin; Wu, Haohao
• Is Part Of: Journal of environmental science and health. Volume 37:Number 2(2019)
• Page Start: 55
• Page End: 66
• Publication Date: 2019-04-03
• Subjects: Gold nanoparticles -- catalase mimetic -- Lactobacillus -- hydrogen peroxide -- foodborne pathogens; Carcinogenesis -- Periodicals; Pollution -- Environmental aspects -- Periodicals; Environmentally induced diseases -- Periodicals; Environmental Health -- periodicals; Carcinogens, Environmental -- periodicals; Hazardous Substances -- periodicals; 616.994071
• DOI: 10.1080/10590501.2019.1591698
• Languages: English
• ISSNs: 1059-0501

Abstract

Abstract: Gold nanoparticles (AuNPs) have been previously shown to induce gut dysbiosis during colitis in mice, but the underlying mechanism is not clear yet. Here, we evaluated the effects of AuNPs (5 nm diameter, coated with tannic acid, polyvinylpyrrolidone or citrate) on H2 O2 accumulation and pathogen antagonization by an intestinal strain of Lactobacillus gasseri under aerobic cultural conditions. AuNPs (0.65 μg/mL) reduced over 50% of H2 O2 accumulation by L. gasseri, and significantly inhibited the antagonistic action of L. gasseri on growth of four foodborne enteric pathogens, i.e. Salmonella enterica serovar Typhimurium, Escherichia coli, Listeria monocytogenes, and Staphylococcus aureus in associative cultures.