Sodium excretion and health-related quality of life: the results from the Korea National Health and Nutrition Examination Survey 2010–2011. Issue 11 (November 2018)

• Record Type: Journal Article
• Authors: Choi, Hye; Lee, Kyu-Beck; Kim, Hyang; Hyun, Young
• Is Part Of: European journal of clinical nutrition. Volume 72:Issue 11(2018)
• Page Start: 1490
• Page End: 1496
• Publication Date: 2018-11
• Subjects: Nutrition -- Periodicals; Nutrition disorders -- Periodicals; Nutritionally induced diseases -- Periodicals; 612.3
• DOI: 10.1038/s41430-018-0090-5
• Languages: English
• ISSNs: 0954-3007

Abstract

Abstract Background/objectives Little is known about the effect of sodium intake on health-related quality of life (HR-QOL). In this study, we investigated the association between estimated 24-h urine sodium and HR-QOL in Korean adults. Subjects/methods In this cross-sectional study, we analyzed 10, 672 participants from Korea National Health and Nutrition Examination Survey (KNHANES) 2010~2011. To assess sodium intake, 24-h urine sodium excretion was estimated from random urine sodium and creatinine using the Kawasaki formula. HR-QOL was assessed using EQ-5D (EuroQol five-dimension) index calculated from Korean version of the EQ-5D questionnaire. Low HR-QOL was defined as the lowest quartile of the EQ-5D index. Participants were divided into three groups according to their estimated 24-h urine sodium level (low, <2.0 g/day; moderate, 2.0~3.9 g/day; high, >4.0 g/day). Results Adjusted means of EQ-5D index were 0.975, 0.995, and 0.991 in the low, moderate, and high estimated 24-h urine sodium group, respectively (P = 0.003 for low vs. moderate, P = 0.078 for high vs. moderate). In a multiple logistic analysis, the odds ratio (OR) for low EQ-5D index in the low estimated 24-h urine sodium group compared to the moderate group was 1.87 (95% confidence interval (CI), 1.33–2.64;P < 0.001). The OR in the high estimated 24-h urine sodium group compared to the moderate group was 1.09 (95% CI, 0.95–1.24;P = 0.218). Conclusions Low estimated 24-h urine sodium rather than high estimated 24-h urine sodium was associated with low HR-QOL in representative Korean adults. Further studies are warranted to verify the effect of sodium intake on HR-QOL and the adequate-level sodium restriction in terms of HR-QOL.