Is earlier better for melanoma checkpoint blockade?. (November 2018)
- Record Type:
- Journal Article
- Title:
- Is earlier better for melanoma checkpoint blockade?. (November 2018)
- Main Title:
- Is earlier better for melanoma checkpoint blockade?
- Authors:
- Robert, Caroline
- Abstract:
- Abstract A neoadjuvant approach relying on the administration of combined anti-CTLA-4–anti-PD-1 treatment before lymph node surgery is evaluated in two phase 1 trials. Encouraging clinical, pathological and immunological responses to neoadjuvant therapy were observed, suggesting that this concept warrants further exploration; however, any future approach must address the unacceptably high toxicity of the regimens evaluated in these trials.
- Is Part Of:
- Nature medicine. Volume 24:Number 11(2018)
- Journal:
- Nature medicine
- Issue:
- Volume 24:Number 11(2018)
- Issue Display:
- Volume 24, Issue 11 (2018)
- Year:
- 2018
- Volume:
- 24
- Issue:
- 11
- Issue Sort Value:
- 2018-0024-0011-0000
- Page Start:
- 1645
- Page End:
- 1648
- Publication Date:
- 2018-11
- Subjects:
- Pathology, Molecular -- Periodicals
Molecular biology -- Periodicals
610.724 - Journal URLs:
- http://www.nature.com/nm/ ↗
http://www.nature.com/ ↗ - DOI:
- 10.1038/s41591-018-0250-0 ↗
- Languages:
- English
- ISSNs:
- 1078-8956
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 6047.030000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 10993.xml