ArraySearch: A Web-Based Genomic Search Engine. (4th March 2012)

• Record Type: Journal Article
• Authors: Wilson, Tyler J.; Ge, Steven X.
• Other Names: Dunham Ian Academic Editor.
• Is Part Of: Comparative and functional genomics. Volume 2012(2012)
• Publication Date: 2012-03-04
• Subjects: Genomics -- Periodicals; Genomes -- Periodicals; Cytogenetics -- Periodicals; 572.86
• DOI: 10.1155/2012/650842
• Languages: English
• ISSNs: 1531-6912

Abstract

Abstract : Recent advances in microarray technologies have resulted in a flood of genomics data. This large body of accumulated data could be used as a knowledge base to help researchers interpret new experimental data. ArraySearch finds statistical correlations between newly observed gene expression profiles and the huge source of well-characterized expression signatures deposited in the public domain. A search query of a list of genes will return experiments on which the genes are significantly up- or downregulated collectively. Searches can also be conducted using gene expression signatures from new experiments. This resource will empower biological researchers with a statistical method to explore expression data from their own research by comparing it with expression signatures from a large public archive.