Improved antibacterial performance using hydrogel-immobilized lysozyme as a catalyst in water. Issue 35 (28th June 2019)

• Record Type: Journal Article
• Authors: Ye, Yuemei; Klimchuk, Stanislav; Shang, Mingwei; Niu, Junjie
• Is Part Of: RSC advances. Volume 9:Issue 35(2019)
• Page Start: 20169
• Page End: 20173
• Publication Date: 2019-06-28
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c9ra02464f
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : Hydrogel-immobilized lysozyme for antibacterial membrane modification. Abstract : Silver nanoparticle-based catalysts are used extensively to kill bacteria in drinking water treatment. However secondary contamination and their high cost require scientists to seek alternatives with non-toxicity, high activity and low cost. In this article, we develop a new hydrogel-immobilized lysozyme (h-lysozyme) that shows excellent antibacterial performance, including high activity duration of up to 55 days, inhibition efficiency as high as 99.4%, good recycling capability of up to 11 cycles, a wide temperature window and extremely low concentration. The immobilized lysozyme displayed greatly improved bacterial inhibition with both Gram-negative E. coli and Gram-positive B. subtilis, which enables broad antibacterial applications in various water systems. In parallel, the non-toxic structure and high stability of the h-lysozyme without additional contamination make it a promising alternative to nanoparticle catalysts fur use in drinking water purification.