Genomic features, phylogenetic relationships, and comparative genomics of Elizabethkingia anophelis strain EM361-97 isolated in Taiwan. Issue 1 (December 2017)

• Record Type: Journal Article
• Authors: Lin, Jiun-Nong; Lai, Chung-Hsu; Yang, Chih-Hui; Huang, Yi-Han; Lin, Hsi-Hsun
• Is Part Of: Scientific reports. Volume 7:Issue 1(2017)
• Page Start: 1
• Page End: 8
• Publication Date: 2017-12
• Subjects: Natural history -- Research -- Periodicals; Biology -- Research -- Periodicals; Physical sciences -- Research -- Periodicals; Earth sciences -- Research -- Periodicals; Environmental sciences -- Research -- Periodicals; 502.85
• DOI: 10.1038/s41598-017-14841-8
• Languages: English
• ISSNs: 2045-2322

Abstract

Abstract Elizabethkingia anophelis has become an emerging infection in humans. Recent research has shown that previous reports ofE. meningoseptica infections might in fact be caused byE. anophelis . We aimed to investigate the genomic features, phylogenetic relationships, and comparative genomics of this emerging pathogen.Elizabethkingia anophelis strain EM361-97 was isolated from the blood of a cancer patient in Taiwan. The total length of the draft genome was 4, 084, 052 bp. The whole-genome analysis identified the presence of a number of antibiotic resistance genes, which corresponded with the antibiotic susceptibility phenotype of this strain. Based on the average nucleotide identity, the phylogenetic analysis revealed thatE. anophelis EM361-97 was a sister group toE. anophelis FMS-007, which was isolated from a patient with T-cell non-Hodgkin's lymphoma in China. Knowledge of the genomic characteristics and comparative genomics ofE. anophelis will provide researchers and clinicians with important information to understand this emerging microorganism.