The Rare Association of Cleft Lip and/or Palate and Wilms Tumor. (September 2019)

• Record Type: Journal Article
• Authors: Theng, Elizabeth; Tracy, Meghan; Hughes, Susan Starling; Kaye, Alison
• Is Part Of: Cleft palate-craniofacial journal. Volume 56:Number 8(2019)
• Page Start: 1096
• Page End: 1106
• Publication Date: 2019-09
• Subjects: cleft lip and palate -- Wilms tumor; Cleft palate -- Periodicals; Skull -- Abnormalities -- Periodicals; Cranial manipulation -- Periodicals; Skull -- Abnormalities -- Surgery -- Periodicals; Face -- Abnormalities -- Surgery -- Periodicals; Fente palatine -- Périodiques; Crâne -- Malformations -- Périodiques; Manipulation crânienne -- Périodiques; Crâne -- Malformations -- Chirurgie -- Périodiques; Face -- Malformations -- Chirurgie -- Périodiques; Cleft palate; Cranial manipulation; Face -- Abnormalities -- Surgery; Skull -- Abnormalities; Skull -- Abnormalities -- Surgery; Cleft Lip; Cleft Palate; Facial Bones -- abnormalities; Skull -- abnormalities; Periodicals; Periodicals; Periodicals; 617.522
• DOI: 10.1177/1055665618824440
• Languages: English
• ISSNs: 1055-6656

Abstract

There is currently no recognized connection between the occurrence of cleft lip and/or palate (CL/P) and Wilms tumor (WT). A retrospective review of cleft team records (2001-2015) revealed 3 cases of children, all male, with concomitant diagnoses of CL/P and WT treated at our institution. These patients presented as infants for care of their CL/P, all with additional congenital anomalies, developmental delays, and growth delays. Between the ages of 1 and 4 years, each was diagnosed with WT, which was treated with chemotherapy and partial nephrectomy, +/− radiation, leading to full remission in all cases.