Diffuse cutaneous mastocytosis: Case report and literature review. Issue 6 (6th September 2018)

• Record Type: Journal Article
• Authors: Hosking, Anna‐Marie; Makdisi, Joy; Ortenzio, Francesca; de Feraudy, Sebastien; Smith, Janellen; Linden, Kenneth
• Is Part Of: Pediatric dermatology. Volume 35:Issue 6(2018)
• Page Start: e348
• Page End: e352
• Publication Date: 2018-09-06
• Subjects: mastocytosis -- vesiculobullous disorders; Pediatric dermatology -- Periodicals; Children -- Diseases -- Periodicals; 618.925
• DOI: 10.1111/pde.13651
• Languages: English
• ISSNs: 0736-8046

Abstract

Abstract: A 6‐month‐old boy was referred to our burn unit with a recurrent bullous dermatitis, fever, and emesis, originally diagnosed as staphylococcal scalded skin syndrome (SSSS) at an outside hospital. Infectious workup was negative and shave biopsy revealed a dense, diffuse dermal infiltrate of mast cells, consistent with diffuse cutaneous bullous mastocytosis—a rare variant of cutaneous mastocytosis. Treatment included a prolonged course of corticosteroids and antihistamines. Recognition of this rare form of mastocytosis is important, as it can be easily mistaken for other pediatric bullous diseases and is associated with life‐threatening complications including vasodilation, anaphylactic shock, gastrointestinal bleeding, and death.