Mepitel Film and Mepilex Lite for the prophylaxis and treatment of skin toxicities from breast radiation. (August 2019)

• Record Type: Journal Article
• Authors: Wan, Bo Angela; Chan, Stephanie; Herst, Patries; Yee, Caitlin; Popovic, Marko; Lee, Justin; Lam, Henry; Pon, Kucy; Aljabri, Saleh; Soliman, Hany; Wronski, Matt; Chow, Edward
• Is Part Of: Breast. Volume 46(2019)
• Page Start: 87
• Page End: 89
• Publication Date: 2019-08
• Subjects: Breast cancer -- Radiation dermatitis -- Mepilex lite -- Mepitel film -- Skin toxicity; Breast -- Diseases -- Periodicals; Breast -- Tumors -- Periodicals; Breast -- Periodicals; Electronic journals; Periodicals; 616
• DOI: 10.1016/j.breast.2019.05.012
• Languages: English
• ISSNs: 0960-9776

Abstract

Abstract: Despite the prevalence of radiation dermatitis in breast cancer patients, current practice guidelines for its treatment are limited. We aimed to discuss the quality of evidence for the barrier-forming Mepitel Film for prophylaxis of radiation dermatitis, and argue for further investigation into evidence-based management of skin toxicities. Two studies assessing Mepitel Film were critically evaluated. Both reported that Mepitel Film decreased radiation dermatitis; moreover, patient-reported outcomes significantly favoured Mepitel Film. However, there has not been global adoption of barrier-forming films such as Mepitel, in part due to the absence of multi-centred randomised trials and the heterogeneity of study designs.