A concise synthesis of (+)-goniofufurone, (+)-7-epi-goniofufurone, (+)-crassalactones B and C. Issue 27 (4th July 2019) - Zhang, Yanli
Graphical abstract: Highlights: The first employment ofd -glucono-δ-lactone to synthesize the four styryllactones. Concise and economical synthetic route. One-pot construction of the furanofurone bicyclic framework. Abstract: The concise and efficient synthesis of (+)-goniofufurone, (+)-7- epi -goniofufurone, (+)-crassalactones B and C were achieved in 6 to 7 steps from the knownd -glucono-δ-lactone derivative9 . An acid-mediated cascade cyclization was employed to construct the furanofurone bicyclic framework in one-pot.