Recurrent hypoglycemia, a rare case of insulin autoimmune syndrome in a young African American male. Issue 3 (May 2019)

• Record Type: Journal Article
• Authors: Jendi, M.R.; Tiwari, N.; Karim, I.
• Is Part Of: Diabetes & metabolic syndrome. Volume 13:Issue 3(2019)
• Page Start: 2320
• Page End: 2321
• Publication Date: 2019-05
• Subjects: Insulin autoimmune syndrome (IAS) -- Insulin autoantibodies (IAA) -- Hypoglycemia; Diabetes -- Periodicals; Metabolism -- Disorders -- Periodicals; Diabetes Mellitus -- Periodicals; Metabolic Diseases -- Periodicals; Diabète -- Périodiques; Métabolisme, Troubles du -- Périodiques; Endocrinologie -- Périodiques; Diabète -- Physiopathologie -- Périodiques; Diabetes; Metabolism -- Disorders; Electronic journals; Periodicals; 616.462
• DOI: 10.1016/j.dsx.2019.05.009
• Languages: English
• ISSNs: 1871-4021

Abstract

Abstract: Insulin autoimmune syndrome (IAS) is an uncommon cause of spontaneous hypoglycemia from hyperinsulinemia due to autoantibodies against endogenous insulin (Jian-Ping Chu, 2016). These individuals have no prior exposure to exogenous insulin. We report a case of a 35-year-old African American male, who presented to Vaughn Regional Medical Center in Selma, AL, after he was found to have seizures from hypoglycemia, with a blood sugar of 63 on presentation. He was never diagnosed with diabetes in the past, nor did he have a history of seizure disorder. He continued to be hypoglycemic during the initial period of his hospital stay. His fasting insulin level was 27 mIU/l (normal is less than 25, with presence of insulin autoantibodies (IAA), and a negative workup otherwise. This led us to include IAS as one of our differentials for his hypoglycemia.