18F-FDG PET/CT in an Atypical Case of Relapsed IgG4-Related Disease Presenting as Inflammatory Pseudotumor in Gall Bladder Fossa With Extensive Disease Involvement. (October 2018)

• Record Type: Journal Article
• Authors: Vadi, Shelvin Kumar; Kumar, Rajender; Mittal, Bhagwant Rai; Parihar, Ashwin Singh; Singh, Harmandeep; Singh, Shashank; Rana, Surinder
• Is Part Of: Clinical nuclear medicine. Volume 43:Number 10(2018)
• Publication Date: 2018-10
• Subjects: IgG4-RD -- FDG PET/CT -- inflammatory pseudotumor -- hepatic infiltration -- relapse -- response evaluation; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000002214
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: Immunoglobulin G4–related disease (IgG4-RD) with multisystem involvement is known to mimic various malignancies and can be diagnosed with high clinical suspicion. We hereby report an atypical case of IgG4-RD, who presented as an inflammatory pseudotumor resembling gall bladder malignancy with hepatic, omental, and subcutaneous involvement. The characteristic tracer uptake pattern described on FDG PET/CT may not be always present in IgG4-RD, especially in the setting of postabdominal surgery. FDG PET/CT revealed the disease progression despite glucocorticoids and aided in response evaluation after second-line drug, rituximab.