Accuracy of Xpert Mtb/Rif Ultra for the Diagnosis of Pulmonary Tuberculosis in Children. Issue 10 (October 2018)

• Record Type: Journal Article
• Authors: Nicol, Mark P.; Workman, Lesley; Prins, Margaretha; Bateman, Lindy; Ghebrekristos, Yonas; Mbhele, Silindile; Denkinger, Claudia M.; Zar, Heather J.
• Is Part Of: Pediatric infectious disease journal. Volume 37:Issue 10(2018)
• Publication Date: 2018-10
• Subjects: tuberculosis -- diagnosis -- children -- Xpert -- Ultra; Communicable diseases in children -- Periodicals; Infection in children -- Periodicals; 618.929
• DOI: 10.1097/INF.0000000000001960
• Languages: English
• ISSNs: 0891-3668

Abstract

Abstract : We determined the accuracy of the new Xpert MTB/RIF Ultra assay for diagnosis of pulmonary tuberculosis in children, using banked-induced sputum. Sensitivity and specificity were 75.3% and 96.9%, respectively, compared with a culture result from the same specimen. Of those children with microbiologically confirmed tuberculosis (positive Xpert, Ultra or culture), Xpert detected 63.2%, Ultra 73.7% and culture 82.9%.