Outcomes of regional anesthesia in cancer patients. Issue 5 (October 2018)

• Record Type: Journal Article
• Authors: Cata, Juan P.
• Is Part Of: Current opinion in anaesthesiology. Volume 31:Issue 5(2018:Oct.)
• Publication Date: 2018-10
• Subjects: cancer recurrence -- regional anesthesia -- survival; Anesthesiology -- Periodicals; Anesthesiology -- Indexes; Anesthesiology -- Periodicals; Review Literature -- Indexes; Review Literature -- Periodicals; Anesthesiology; Periodicals; 617.9605
• DOI: 10.1097/ACO.0000000000000636
• Languages: English
• ISSNs: 0952-7907

Abstract

Abstract : Purpose of review: To summarize the current evidence on the impact of regional anesthesia or analgesia on cancer recurrence. Recent findings: Preclinical investigations suggest that regional anesthesia could have a positive impact on reducing cancer growth and progression. Regional anesthesia is also associated with better immunological and stress-related outcomes in patients undergoing major oncological surgery. Most recent retrospective studies do not show any benefit of regional anesthesia or analgesia on cancer recurrence or recurrence-free survival. Summary: The available clinical evidence does not support the use of any anesthesia technique to improve the cancer-related survival after major oncological surgery. The results from four randomized controlled trials will shed light on this critical topic in perioperative medicine.