New Insights on Properties and Spatial Distributions of Skeletal Stem Cells. (3rd June 2019)

• Record Type: Journal Article
• Authors: Liu, Jun-qi; Li, Qi-wen; Tan, Zhen
• Other Names: Ogasawara Toru Guest Editor.
• Is Part Of: Stem cells international. Volume 2019(2019)
• Publication Date: 2019-06-03
• Subjects: Stem Cells -- Periodicals; Stem Cells -- Therapeutic use -- Periodicals; Stem Cells -- Transplantation -- Periodicals; 616.0277405
• DOI: 10.1155/2019/9026729
• Languages: English
• ISSNs: 1687-966X

Abstract

Abstract : Skeletal stem cells (SSCs) are postnatal self-renewing, multipotent, and skeletal lineage-committed progenitors that are capable of giving rise to cartilage, bone, and bone marrow stroma including marrow adipocytes and stromal cells in vitro and in an exogenous environment after transplantation in vivo. Identifying and isolating defined SSCs as well as illuminating their spatiotemporal properties contribute to our understating of skeletal biology and pathology. In this review, we revisit skeletal stem cells identified most recently and systematically discuss their origin and distributions.