Colloid cyst and multiple meningiomata in Gorlin syndrome. (January 2018)

• Record Type: Journal Article
• Authors: Li, Yan-Lin; Kwok, Stephen Kai-Yan; Shiu, Kenneth Chun-Kit
• Is Part Of: Journal of clinical neuroscience. Volume 47(2018)
• Page Start: 157
• Page End: 159
• Publication Date: 2018-01
• Subjects: Brain -- Surgery -- Periodicals; Neurosciences -- Periodicals; Nervous system -- Surgery -- Periodicals; Brain -- surgery -- Periodicals; Neurosurgical Procedures -- Periodicals; Neurosciences -- Periodicals; Electronic journals; 616.8
• DOI: 10.1016/j.jocn.2017.10.083
• Languages: English
• ISSNs: 0967-5868

Abstract

Highlights: Gorlin syndrome is characterized by malformations and tumours from PTCH1 mutations. Common tumours include basal cell carcinoma, medulloblastoma and fibroma. This is the first case where colloid cyst and meningioma are both associated. Abstract: A middle-aged man presented with syncope and confusion. Neuroimaging revealed a third ventricular mass with obstructive hydrocephalus and bilateral convexity meningiomata. The masses were excised and pathology showed a colloid cyst and WHO grade 1 meningiomata respectively. Multisystem workup confirmed Gorlin syndrome. To our knowledge, this is the fourth reported case of Gorlin syndrome associated with colloid cyst, and the first case where multiple meningiomata are also present.