Metastasis of Ewing's sarcoma to the thyroid gland: A case report. (October 2018)

• Record Type: Journal Article
• Authors: Appachi, Swathi; Meleca, Joseph B.; Krakovitz, Paul
• Is Part Of: International journal of pediatric otorhinolaryngology. Volume 113(2018:Oct.)
• Page Start: 26
• Page End: 28
• Publication Date: 2018-10
• Subjects: Thyroid -- Metastasis -- Immunotherapy; Otolaryngology -- Periodicals; Pediatrics -- Periodicals; Otolaryngology -- Periodicals; Pediatrics -- Periodicals; Oto-rhino-laryngologie -- Périodiques; Pédiatrie -- Périodiques; 618.9209751
• DOI: 10.1016/j.ijporl.2018.07.020
• Languages: English
• ISSNs: 0165-5876

Abstract

Abstract: Ewing's sarcoma (ES) is an aggressive pediatric malignancy. We present a case of ES with thyroid metastasis. The patient was diagnosed with ES at age 8. Despite aggressive treatment, she suffered disease progression. Surveillance demonstrated a left thyroid lesion. This grew rapidly within 2 months, causing tracheal compression. She underwent hemi-thyroidectomy to prevent airway compromise. Due to her refractory ES, she was enrolled in the Vigil immunotherapy vaccine trial; thus, the specimen was used for vaccine development. This is the first reported case of skeletal ES with metastasis to the thyroid, requiring hemithyroidectomy to prevent airway compromise.