Validity of narrow band imaging in the detection of oral and oropharyngeal malignant lesions: A systematic review and meta‐analysis. Issue 7 (9th March 2019)

• Record Type: Journal Article
• Authors: Ansari, Umair H.; Wong, Eugene; Smith, Murray; Singh, Narinder; Palme, Carsten E.; Smith, Mark C.; Riffat, Faruque
• Is Part Of: Head & neck. Volume 41:Issue 7(2019)
• Page Start: 2430
• Page End: 2440
• Publication Date: 2019-03-09
• Subjects: erythroplakia -- leukoplakia -- malignant lesions -- narrow band imaging -- oral lesions; Head -- Diseases -- Periodicals; Neck -- Diseases -- Periodicals; Head -- Periodicals; Neck -- Periodicals; Face -- Periodicals; 617.51059
• DOI: 10.1002/hed.25724
• Languages: English
• ISSNs: 1043-3074

Abstract

Abstract: Background: This meta‐analysis describes the validity of narrow band imaging (NBI) in the assessment of suspicious oral lesions. Methods: Medline, EMBASE, and Scopus were searched for trial studies comparing NBI with conventional modalities in the oral cavity (OC) and oropharynx (OP) for the detection of dysplastic and malignant change. Results: Seven studies were found, and generally supported the utility of NBI in different clinical settings, although there were exceptions. Pooled data from 4 studies of NBI validity demonstrated high summary specificity and sensitivity for a wide range of suspicious lesions of the OC or OP (75.7% with 95% CI 65.1%‐83.9%, and 91.5% with 95% CI 81.8%‐96.3%, respectively). Summary positive likelihood ratio (LR+) was 8.91 (95% CI 4.1‐19.6) and 0.27 (95% CI 0.18‐0.39), respectively. Conclusions: NBI is a promising diagnostic and surveillance tool for suspicious lesions in the OC or OP; however, higher powered studies will define precise NBI criterion and clinical recommendations.