Travel-related health events and their risk factors in HIV-infected sub-Saharan migrants living in France and visiting their native country: The ANRS VIHVO cohort study. Issue 29 (May 2019)

• Record Type: Journal Article
• Authors: Bentata, Michele; Fantin, Bruno; Goujard, Cécile; Matheron, Sophie; Launay, Odile; Le Moing, Vincent; Lortholary, Olivier; Consigny, Paul- Henri; Saada, Matthieu; Katlama, Christine; Simon, Anne; Arvieux, Cédric; Campa, Pauline; Girard, Pierre-Marie; Khuong, Marie-Aude; Molina, Jean-Michel; Lascoux-Combe, Caroline; Rey, David; Rondeau, Murielle; Pialoux, Gilles; Couzigou, Carine; Vittecoq, Daniel; Patey, Olivier; Morlat, Philippe; Duong, Michel; Chavanet, Pascal; Pistone, Thierry; Ouattara, Eric; Gabillard, Delphine; Lele, Nathalie; Duvignaud, Alexandre; Cordel, Hugues; Malvy, Denis; Bouchaud, Olivier; Abgrall, Sophie;
• Is Part Of: Travel medicine and infectious disease. Issue 29(2019)
• Page Start: 40
• Page End: 47
• Publication Date: 2019-05
• Subjects: Migrant -- HIV infection -- Travel -- Health event -- Visiting friends and relatives -- Sub-Saharan Africa; Travel -- Health aspects -- Periodicals; Communicable diseases -- Periodicals; Tropical medicine -- Periodicals; 610.5
• DOI: 10.1016/j.tmaid.2019.03.010
• Languages: English
• ISSNs: 1477-8939

Abstract

Abstract: Background: Literature on health events in HIV-infected travellers is scarce, particularly in sub-Saharan African (SSA) migrants. Methods: We investigated health events in HIV-infected SSA migrants living in France during and after travel to their native country. All had a pre-travel plasma viral load (pVL) below 200 copies/mL and were on stable combined antiretroviral therapy (cART). Logistic regression models were used to assess the risk factors for at least one adverse health event or febrile event. Results: Among 264 HIV migrants, pre-travel median CD4 count was 439/mm3 and 27 migrants (6%) experienced a low-level viremia between 50 and 200 copies/mL. One hundred (38%) experienced at least one event (13 experienced two events). The most common events were gastrointestinal, including diarrhoea (n = 29, 26%), respiratory events (n = 20, 18%), and malaria (n = 17, 15%; 1 death). In multivariable analysis, a pre-travel low-level viremia and a lack of pre-travel medical advice significantly increased the risk for any event (OR 4.31, 95% CI, 1.41–13.1; and OR 3.62, 95% CI, 1.38–9.47; respectively). A lack of pre-travel advice significantly increased the risk for febrile event. Conclusions: Early and tailored counselling on pre-travel medical advice regarding diarrhoea and vector-borne diseases prophylactic measures in HIV-infected SSA migrants should be emphasised before travel to Africa.