A gold-catalyzed facile intramolecular rearrangement and cyclization sequence for synthesis of 2, 5-dihydrofurans. Issue 24 (3rd June 2019)

• Record Type: Journal Article
• Authors: Sunil, Komalla; Thummala, Yadagiri; Dalovai, Purnachandar; Balasubramanian, Sridhar; Karunakar, Galla V.
• Is Part Of: Organic & biomolecular chemistry. Volume 17:Issue 24(2019)
• Page Start: 6015
• Page End: 6024
• Publication Date: 2019-06-03
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c9ob00756c
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : An efficient gold-catalyzed intramolecular rearrangement and cyclization protocol was developed for synthesis of 2, 5-dihydrofuran derivatives via formation of a new C–C and C–O bond with a quaternary centre. Abstract : An efficient gold-catalyzed intramolecular rearrangement and cyclization protocol was developed for synthesis of 2, 5-dihydrofuran derivatives from O -propargyl β-enaminones. In this organic transformation new C–C and C–O bonds are formed under mild reaction conditions; this includes the formation of a quaternary centre.